Interleukin-6-dependent influence of nociceptive

on poly-L-lysine- (200 μg/ml; Sigma-Aldrich) coated glass coverslips and kept in a .... mice (broken line, r = 0.267, p = 0.457), n = 10–11 per gro...

0 downloads 0 Views 2MB Size

Recommend Documents

obtained from Charles River Laboratories (Hollister, CA). Several days before surgery, animals were individually housed in standard clear plastic cages in a ...

Bradykinin was administered within about 1 sec or less at intervals of 15-30 min. .... bradykinin-induced pain resembles deep, visceral or protopathic pain more ...

Feb 17, 2010 - electrical test stimuli to quantify and confirm the effects of HFS on the behavioral level. ERPs to .... brated sharp-tipped von Frey monofilament (size: 6.1; target force: 980 mN .... TABLE 1. Medians (and interquartile ranges) of the

Feb 17, 2010 - nociceptive LTP can be elicited in humans after high frequency electrical stimulation (HFS) of. 76 ... at 10 sec interval with an intensity of 20 × detection threshold on the forearm 5 cm distal to. 113 the fossa cubita ... 5 stimulat

Feb 17, 2010 - electrical test stimuli to quantify and confirm the effects of HFS on the behavioral level. ERPs to .... brated sharp-tipped von Frey monofilament (size: 6.1; target force: 980 mN .... TABLE 1. Medians (and interquartile ranges) of the

infusion pump. Changes in intracellular free calcium concentration (intracellular. [Ca2]free) were measured by digital microscopy (Universal; Carl. Zeiss, Inc., Thornwood, NY) equipped ... analyzed using ClampFit software and transferred to Excel spr

May 25, 2016 - Keywords: nociceptive detection, detection threshold, capsaicin, neuroplasticity, computational modeling. 1. INTRODUCTION. The nociceptive system processes pain-related information and its function results from the delicate balance of

Nov 20, 2013 - Pathological changes in axonal function are integral features of many neurological disorders, yet our knowledge of the molecular basis of axonal dysfunction remains limited. Microfluidic chambers (MFCs) can provide unique insight into

Jan 29, 2015 - We used Nociception Coma Scale-Revised (NCS-R) and. Coma Recovery Scale (CRS-R) for clinical evaluation of pain perception and ...

Apr 22, 2015 - ... Montserrat Vallverdú1,2,3, Xavier Borrat4,5, Jose Fernando Valencia6, ... Biomedical Engineering Research, Pau Gargallo 5, 08028, ...

Nov 14, 2016 - Abstract: Specialized receptors belonging to the transient receptor potential (TRP) family of ligand-gated ion channels constitute the critical detectors and transducers of pain-causing stimuli. Nociceptive TRP channels are predominant

spinothalamic tract (STT) and the dorsal column (DC) [22,26]. STT neurons excited by visceral nociceptive stimuli are located in the dorsal horn, and postsynaptic dorsal column (PSDC) neurons which conduct visceral nociceptive signals in the DC pathw

Sep 20, 2016 - Keywords: pain; neonate; spinal cord; dorsal horn; synapse; glutamate; ... injury on synaptic signaling in the spinal superficial dorsal horn.

Я 2007 Lippincott Williams & Wilkins. aKorea University Graduate School of Medicine ..... Venkatachalam K, Montell C. TRP Channels. Annu Rev Biochem 2007;.

Li, J., Simone, D. A., & Larson, A. A. (1999). Windup leads to ...... Roosink, M., Buitenweg, J. R., Renzenbrink, G. J., Geurts, A. C., & IJzerman, M. J. (2011). Altered ...

Oct 11, 2016 - resveratrol to the relief of nociceptive and/or pathological pain and its .... Thus, resveratrol may suppress glutamatergic excitatory synaptic.

Jul 7, 2010 - tures increasing with increasing laser power, which is similar to that we ... 0.45. 0.35. 0.55. 0.65. 0.1. 0.2. 0.3. 0.4. 0.5. 0.6. 0.7. Time (s). & 15s, 350mA simulus. & Threshold ..... using Chart 5 and Microsoft Excel. At the end of 

ceptive transmission from the medullary raphe nuclei in the rat. descending .... caudal to the lumbar laminectomy and a pool for agar (1.75% in saline) was made ...

Nociceptive withdrawal reflexes (NWRs) were studied in adult .... amplitude (0.5–1.5 mV) δ waves (1–3 Hz), which demonstrated a coma- .... Scale bar, 20 mm.

Differential Diagnosis: Nociceptive and Neuropathic. Pain -. Prof Victor ..... Tramadol. • Used for moderate pain. • May cause dizziness, nausea, and headache ...

We have previously shown in anesthetized rats that electrical or chemical stimulation of the .... computer-assisted analysis of the data. ...... mesolimbic reward circuits. J Neurosci 19: ... Kelley AE, Bakshi VP, Delfs JM, and Lang CG. Cholinergic .

knee joint (n. 62) typically ... preferentially to noxious mechanical stimulation of deep tissue (n. 58). .... conditioned and stress-induced analgesia (Fox and Sorenson. 1994 ..... best described stimulus-response curves for graded mechanical.

Nov 4, 2015 - 1 Department of Anesthesiology, Stanford University School of .... the LINE-1 global methylation site, which is correlated with pain ..... Zhou XL, Yu LN, Wang Y, Tang LH, Peng YN, Cao JL, et al. .... 2003; 304(1):102–8. doi: 10. ....

(C) Intraplantar pre-injection of 10 μg capsaicin (n = 15) reduced the licking time of mice induced by 2% formalin, compared to vehicle group (n .... (C) Intraplantar injection of 100 μg capsaicin could mildly reduce mechanical allodynia 7 days aft