Macrophage Biocompatibility of CoCr Wear Particles Produced ... - MDPI

May 8, 2018 - Gregorio del Amo 8, 28040 Madrid, Spain; ...... Dorr, L.D.; Bloebaum, R.; Emmanual, J.; Meldrum, R. Histologic, ... Ponthiaux, P.; Wenge...

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The particles became incorporated in synovial tissue and persisted in the synovial fluid for many months. Smaller particles were phagocytosed by intimal cells, macrophages, multinucleate giant cells and fibroblasts; larger particles remained extracel

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