The Hedgehog signaling pathway in ovarian

treatment decreases Gli1 localization in the nucleus compared to non-treated .... polyclonal anti-Gli1 (Santa Cruz; sc-20687) (24) and rabbit ..... Hh...

2 downloads 0 Views 704KB Size

Recommend Documents

Jan 9, 2013 - Rosen, D.G.; Yang, G.; Liu, G.; Mercado-Uribe, I.; Chang, B.; Xiao, X.S.; Zheng, J.; Xue, F.X.;. Liu, J. Ovarian cancer: Pathology, biology, and ...

Jul 30, 2015 - The hedgehog signaling pathway is a mechanism that directs the development of ..... Reviews: Molecular Cell Biology 6 (2005): 306?17. 7.

Oct 15, 2006 - Abstract The Hedgehog (Hh) pathway is a signaling cascade that directs patterning in most animals ... comprehensive review of Hh signaling).

Oct 15, 2006 - Genentech, Inc., 460 Point San Bruno Boulevard, South San Francisco, CA 94080. ..... Frank-Kamenetsky M, Zhang XM, Bottega S, et al.

Jul 29, 2014 - 1 Department of Gastroenterology, the Tenth People's Hospital of Shanghai, ...... novel mechanistic insight on transcriptional regulation of meta-.

Feb 25, 2017 - Research Paper. Hedgehog signaling pathway regulates ovarian cancer ... was approved by the Institutional Review Board of the Second ...

Deubiquitination of Ci/Gli by Usp7/HAUSP regulates Hedgehog. Signaling .... which Serines on 212, 219, 555, 888 and 1113 replaced by Alanines. Of note, Ci.

Feb 7, 2016 - Keywords: sonic hedgehog signaling pathway, PI-3 kinase, c-Met, Snail, cell motility ..... review conducted by another journal and the authors'.

Jun 1, 2016 - Gastroenterology Department, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte (CHLN), ... roughly one billion subjects worldwide [1]. .... then moves along the cilia in a retrograde fashion via a dynein motor ..... Pathi, S.; Pag

Jan 15, 2014 - Disrupting the Indian hedgehog signaling pathway in vivo attenuates ..... proved by the Institutional Review Board at Rhode Island. Hospital ...

Keywords: colorectal cancer, Hedgehog signaling pathway, cancer therapy ... In this review, we will go through previous literature on the Hh signaling pathway.

Sep 17, 2018 - Kanagawa 259-1193, Japan. 2 Department of Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro.

2015; 100:e102–e105. [PubMed: 25527561] ... Philips GM, Chan IS, Swiderska M, Schroder VT, Guy C, Karaca GF, Moylan C, Venkatraman T,. Feuerlein S, Syn ...

May 3, 2010 - facies and calcification of the falx cerebri and bony abnormalities may occur (bifid ribs, ... stem cells or progenitor cells in this portion of the brain. ..... Bryden M, Evans H, Keeler R, Cyclopia in sheep caused by plant teratogens.

Some researchers have proposed that the sonic hedgehog (Shh) pathway ... signaling pathway may be a potential therapeutic strategy for hepatocarcinogenesis. ...... OncoTargets and Therapy is an international, peer-reviewed, open access.

May 20, 2015 - Scientific REPORTS | 5:10290 | DOi: 10.1038/srep10290 www.nature.com/scientificreports. Indian Hedgehog signaling pathway members are ...

Aberrant activation of hedgehog signaling pathway in ovarian cancers: effect on ... In the absence of ligands, the pathway is inactive. The transmembrane protein receptor Patched functions as a tumor suppressor that inhibits Smoothened (Smo) ...... d

Feb 27, 2017 - Hippo signaling pathway • YAP1 • Ovarian germline stem cells • Ovarian ..... we discovered that three key molecules in the Hippo signaling.

Aug 13, 2017 - [29] J. M. Oatley and R. L. Brinster, “The germline stem cell niche ... 3063, 2006. [41] T. R. Hartman, D. Zinshteyn, H. K. Schofield, E. Nicolas, A.

May 22, 2015 - An essential role for Hedgehog (Hh) signaling in human cancer has been established beyond doubt. At present, targeting Hh signaling has mainly been investigated with SMO inhibitors. Unfortunately, resistance against currently used. SMO

Jun 19, 2012 - The Hedgehog (Hh) signaling pathway regulates embryonic .... example, SMO has been found to activate the RhoA and Rac1 ... The SMO antagonist PF-04449913 (Pfizer) has also provided encouraging early results in.

Sep 15, 2017 - model for hereditary tyrosinemia type I (HT1) ... Different types of mice divided into four ... ed to NTBC withdrawal; 3) Fah-/- mice by NTBC.

Jun 19, 2012 - The Hedgehog (Hh) signaling pathway regulates embryonic development and may be aberrantly activated in .... For example, SMO has been found to activate the ... (GDC-0449, LDE225, PF04449913, and TAK-441; refs. 34–.

Nov 20, 2017 - In this review, we provide a current understanding of the role of the HH ..... 6 of 19 during hair follicle development. Figure 3. The roles of the HH signaling ..... Bai, C.B.; Auerbach, W.; Lee, J.S.; Stephen, D.; Joyner, A.L. Gli2,